CAIS Aptamer G-Iodine — Minimal Kernel Diagram v1.0
A compact builder-facing view of Aptamer G-Iodine as the minimal molecular kernel (M0) inside the CAIS / Sal-Meter stack: where it sits, what it gates, how state-transition events become measurable signals, and how those signals move downstream into canonical indices under governance constraints.
A signal-gating page, not a meaning-making page
M0 is not “meaning.” M0 is signal gating.
This page exists to help an engineer, PI, or technical lead understand the smallest stable molecular gate in the CAIS / Sal-Meter stack. It does not redefine CAIS, Sal-Meter, OE / RE / EE, VCE / CRI / CFI, or any compliance boundary.
Why Aptamer G-Iodine is treated as M0
Minimal
The smallest controlled gate that can turn molecular state transitions into repeatable signal events.
Controllable
It runs under a bounded interface environment rather than open-ended interpretation.
Signal-producing
Binding, conformational, and redox transitions become transducible events.
Non-therapeutic
It sits inside a cartridge / measurement chamber as a sensing interface, not as treatment.
What the molecule gates
Iodine oxidation logic
Iodine redox behavior provides one side of the molecular switching logic.
GSH / GSSG sensing
The glutathione axis provides the paired redox-state sensing side of the interface.
State transitions as measurable events
Binding, conformation, and redox transitions are treated as signal events first. Clinical meaning is not assigned at Layer 0.
How M0 moves downstream
Molecular Interface
Input: controlled biological / chemical state. Output: signal-ready events with no clinical meaning attached.
Signal + Metric Pipeline
Transduction → preprocessing → feature extraction → stability checks.
Index Computation
OE / RE / EE → VCE / CRI / CFI under CAIS-defined computation and validation workflow.
Interpretation & Governance
Validation workflow, compliance boundary, multi-team checks, and misuse control sit downstream of M0.
External cartridge / chamber view
Layer 0 runs inside the cartridge as a non-therapeutic interface. The device measures molecular state transitions and outputs signals for downstream processing, not clinical meaning.